Melanoma Molecular Maps Projects


The IPD is a multicenter database, which gathers anonymized information about clinical and histopathological features as well as availability of biological material regarding patients with cutaneous melanoma enrolled by centers that participate in this project.
A systematic collection of the scientific knowledge regarding the development of targeted therapy for melanoma. Since data are gathered in a computationally compatible fashion, the database can be utilized for the identification of prevalent therapeutic hypotheses based on the available evidence and for ranking treatments based on the patient's molecular profile (drug ranking system).
Inspired to the principles of functional interactomics, this is a collection of schematic figures depicting the molecular pathways involved in cancer development and progression, with particular regard to melanoma. A close-to-hand visual guide to navigate in the ever-growing complexity of cancer molecular biology.

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Melanoma News

Hypofractionated Radiation Therapy for Node-Positive Cutaneous Melanoma.
Mathen P, Debenham BJ, Voroney JP, Banerjee RN
Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2S):S158.
PMID: 27675667 [PubMed - as supplied by publisher]

Does Regional Radiation Therapy Impact Outcome for High-Risk, Node-Positive Cutaneous Melanoma?
Parekh A, Strom T, Naghavi AO, Caudell JJ, Zager JS, Messina JL, Torres-Roca JF, Sondak VK, Trotti A, Harrison LB
Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2S):S157.
PMID: 27675666 [PubMed - as supplied by publisher]

Clinical Outcomes in Stage III Cutaneous Melanoma Treated With Adjuvant Radiation Therapy.
Mathen P, Debenham BJ, Voroney JP, Banerjee RN
Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2S):E714.
PMID: 27675439 [PubMed - as supplied by publisher]

Clinical Significance of BRAF V600E Mutational Status in Capsular Nevi of Sentinel Lymph Nodes in Patients with Primary Cutaneous Melanoma.
Siroy AE, Aung PP, Torres-Cabala CA, Tetzlaff MT, Nagarajan P, Milton DR, Curry JL, Ivan D, Prieto VG
Hum Pathol. 2016 Sep 22;():.
PMID: 27666765 [PubMed - as supplied by publisher]

appendix 2: Cutaneous melanoma (2): eUpdate published online September 2016 (
Dummer R, Keilholz U, ESMO Guidelines Committee
Ann Oncol. 2016 Sep;27(suppl 5):v136-v137.
PMID: 27664250 [PubMed - as supplied by publisher]

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