Melanoma Molecular Maps Projects



Title: Adhesion molecules & cancer/melanoma: a systematic databank
Legend: Cell surface adhesion molecules play vital roles in numerous cellular processes, including cell growth, differentiation, embryogenesis, immune cell transmigration and response, and cancer metastasis. Adhesion molecules are also capable of transmitting information from the extracellular matrix to the cell. There are four major families of cell adhesion molecules. These are the immunoglobulin (Ig) superfamily cell adhesion molecules (CAMs), integrins, cadherins, and selectins. However, many more adhesion molecules have been identified, as shown in this databank, which is meant to be a comprehensive/ systematic collection of cell adhesion molecules and the relative summary data on their role in cancer (with special regard to melanoma). More detailed information on single molecules (with special regard to their diagnostic/ prognostic / therapeutic potential in the field of oncology) is (or will be) the object of dedicated records in the Biocards database.
Author: The MMMP Team (updated: January 2009)

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