Melanoma Molecular Maps Projects


The IPD is a multicenter database, which gathers anonymized information about clinical and histopathological features as well as availability of biological material regarding patients with cutaneous melanoma enrolled by centers that participate in this project.
A systematic collection of the scientific knowledge regarding the development of targeted therapy for melanoma. Since data are gathered in a computationally compatible fashion, the database can be utilized for the identification of prevalent therapeutic hypotheses based on the available evidence and for ranking treatments based on the patient's molecular profile (drug ranking system).
Inspired to the principles of functional interactomics, this is a collection of schematic figures depicting the molecular pathways involved in cancer development and progression, with particular regard to melanoma. A close-to-hand visual guide to navigate in the ever-growing complexity of cancer molecular biology.

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Melanoma News

Parkinson disease (PARK) genes are somatically mutated in cutaneous melanoma.
Inzelberg R, Samuels Y, Azizi E, Qutob N, Inzelberg L, Domany E, Schechtman E, Friedman E
Neurol Genet. 2016 Jun;2(3):e70.
PMID: 27123489 [PubMed]

Variations in the expression of TIMP1, TIMP2 and TIMP3 in cutaneous melanoma with regression and their possible function as prognostic predictors.
Zurac S, Neagu M, Constantin C, Cioplea M, Nedelcu R, Bastian A, Popp C, Nichita L, Andrei R, Tebeica T, Tanase C, Chitu V, Caruntu C, Ghita M, Popescu C, Boda D, Mastalier B, Maru N, Daha C, Andreescu B, Marinescu I, Rebosapca A, Staniceanu F, Negroiu G, Ion DA, Nikitovic D, Tzanakakis GN, Spandidos DA, Tsatsakis AM
Oncol Lett. 2016 May;11(5):3354-3360.
PMID: 27123116 [PubMed]

Intraocular Inflammation Associated with New Therapies for Cutaneous Melanoma - Case Series and Review.
Fierz FC, Meier F, Chaloupka K, Böni C
Klin Monbl Augenheilkd. 2016 Apr;233(4):540-544.
PMID: 27116532 [PubMed - as supplied by publisher]

Blue Nevus-Like Metastasis of a Cutaneous Melanoma Identified by Fluorescence In Situ Hybridization.
Campa M, Patel M, Aubert P, Hosler G, Witheiler D
Am J Dermatopathol. 2016 Apr 19;():.
PMID: 27097332 [PubMed - as supplied by publisher]

Spatial analysis of incidence of cutaneous melanoma in the Friuli Venezia Giulia region in the period 1995-2005.
Cecconi L, Busolin A, Barbone F, Serraino D, Chiarugi A, Biggeri A, Catelan D
Geospat Health. 2016 Apr 18;11(1):422.
PMID: 27087039 [PubMed - in process]

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